{
  "id": 146005,
  "title": "Gleason Grading system and International Society of Urological Pathology (ISUP) ",
  "url": "/competitions/prostate-cancer-grade-assessment/discussion/146005",
  "author_name": "ⵀⴰⵜⴻⵎ ⵎ'ⵀⴰⵎⴻⴷ ⴰⵎⵉⵏⴻ",
  "post_date": "2020-04-25T13:14:38.632000",
  "votes": 2,
  "comment_count": 1,
  "views": 0,
  "content": "<p><a href=\"https://www.youtube.com/watch?v=vdRDIaZAlOc\">https://www.youtube.com/watch?v=vdRDIaZAlOc</a></p>\n\n<p>Gleason Grading system has undergone several revisions in order to improve reproducibility and prognostic value (7). Most recently, a new grading system has been proposed by the International Society of Urological Pathology (ISUP) (8) and is integrated into the 2016 edition of the WHO classification of Tumor of the Urinary System and Male Genital Organs (9). Major modifications of the ISUP Grade Groups toward the last update in 2010 include defining five distinct Grade Groups based on the Gleason score: Grade Group 1 = Gleason score ≤6, Grade Group 2 = Gleason score 3 + 4 = 7, Grade Group 3 = Gleason score 4 + 3 = 7, Grade Group 4 = Gleason score 8, Grade Group 5 = Gleason scores ≥9\n<a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626925/\">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626925/</a></p>",
  "messages": [
    {
      "id": 820464,
      "postDate": "2020-04-25T13:14:38.633Z",
      "content": "<p><a href=\"https://www.youtube.com/watch?v=vdRDIaZAlOc\">https://www.youtube.com/watch?v=vdRDIaZAlOc</a></p>\n\n<p>Gleason Grading system has undergone several revisions in order to improve reproducibility and prognostic value (7). Most recently, a new grading system has been proposed by the International Society of Urological Pathology (ISUP) (8) and is integrated into the 2016 edition of the WHO classification of Tumor of the Urinary System and Male Genital Organs (9). Major modifications of the ISUP Grade Groups toward the last update in 2010 include defining five distinct Grade Groups based on the Gleason score: Grade Group 1 = Gleason score ≤6, Grade Group 2 = Gleason score 3 + 4 = 7, Grade Group 3 = Gleason score 4 + 3 = 7, Grade Group 4 = Gleason score 8, Grade Group 5 = Gleason scores ≥9\n<a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626925/\">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626925/</a></p>",
      "rawMarkdown": "[https://www.youtube.com/watch?v=vdRDIaZAlOc](https://www.youtube.com/watch?v=vdRDIaZAlOc)\n\nGleason Grading system has undergone several revisions in order to improve reproducibility and prognostic value (7). Most recently, a new grading system has been proposed by the International Society of Urological Pathology (ISUP) (8) and is integrated into the 2016 edition of the WHO classification of Tumor of the Urinary System and Male Genital Organs (9). Major modifications of the ISUP Grade Groups toward the last update in 2010 include defining five distinct Grade Groups based on the Gleason score: Grade Group 1 = Gleason score ≤6, Grade Group 2 = Gleason score 3 + 4 = 7, Grade Group 3 = Gleason score 4 + 3 = 7, Grade Group 4 = Gleason score 8, Grade Group 5 = Gleason scores ≥9\n[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626925/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626925/)",
      "votes": 2
    },
    {
      "id": 820470,
      "postDate": "2020-04-25T13:18:59.673Z",
      "content": "<p>thanks for sharing :)</p>",
      "rawMarkdown": "thanks for sharing :)",
      "votes": 1
    }
  ],
  "comments": [
    {
      "id": 820470,
      "author_name": "Alberto Maria Falletta",
      "author_url": "",
      "post_date": "2020-04-25T13:18:59.673000",
      "content": "<p>thanks for sharing :)</p>",
      "votes": 1,
      "replies": []
    }
  ],
  "raw_markdown_by_id": {
    "820464": "[https://www.youtube.com/watch?v=vdRDIaZAlOc](https://www.youtube.com/watch?v=vdRDIaZAlOc)\n\nGleason Grading system has undergone several revisions in order to improve reproducibility and prognostic value (7). Most recently, a new grading system has been proposed by the International Society of Urological Pathology (ISUP) (8) and is integrated into the 2016 edition of the WHO classification of Tumor of the Urinary System and Male Genital Organs (9). Major modifications of the ISUP Grade Groups toward the last update in 2010 include defining five distinct Grade Groups based on the Gleason score: Grade Group 1 = Gleason score ≤6, Grade Group 2 = Gleason score 3 + 4 = 7, Grade Group 3 = Gleason score 4 + 3 = 7, Grade Group 4 = Gleason score 8, Grade Group 5 = Gleason scores ≥9\n[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626925/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626925/)",
    "820470": "thanks for sharing :)"
  }
}