{
  "id": 154210,
  "title": "Clarification for 4+3 v/s 4+4",
  "url": "/competitions/prostate-cancer-grade-assessment/discussion/154210",
  "author_name": "lincoln",
  "post_date": "2020-05-27T16:02:43.614000",
  "votes": 1,
  "comment_count": 2,
  "views": 0,
  "content": "<p>I am going through the explanation provided in additional resources and cannot comprehend below statement. </p>\n\n<p>\"The minority pattern must account for at least 5% of the total area to be included, e.g. if pattern 3 is less than 5%, the Gleason score 4 + 3 will instead be 4 + 4. Further, the highest grade should always be part of the score. For example, a biopsy that contains 60% Gleason 4, 37% Gleason 3 and 3% Gleason 5 should get a score of 4 + 5 = 9. For details see (Epstein, 2016).\"</p>\n\n<p>Question : pattern 3 &lt; 5% then why gleason score will be 4+4 ? </p>",
  "messages": [
    {
      "id": 864918,
      "postDate": "2020-05-28T09:11:06.173Z",
      "content": "<p>If the minority pattern takes up less than 5% of the tissue, you should not take it into account. In the example, &lt;5% is Gleason 3 and the rest is Gleason 4. In that case the Gleason score will be 4+4 because there is no other significant pattern.</p>\n\n<p>Edit: To clarify further, if there is a minor but higher pattern present (like 3% G5), it should always be included.</p>",
      "rawMarkdown": "If the minority pattern takes up less than 5% of the tissue, you should not take it into account. In the example, &lt;5% is Gleason 3 and the rest is Gleason 4. In that case the Gleason score will be 4+4 because there is no other significant pattern.\n\nEdit: To clarify further, if there is a minor but higher pattern present (like 3% G5), it should always be included.",
      "votes": 3
    },
    {
      "id": 863866,
      "postDate": "2020-05-27T16:02:43.613Z",
      "content": "<p>I am going through the explanation provided in additional resources and cannot comprehend below statement. </p>\n\n<p>\"The minority pattern must account for at least 5% of the total area to be included, e.g. if pattern 3 is less than 5%, the Gleason score 4 + 3 will instead be 4 + 4. Further, the highest grade should always be part of the score. For example, a biopsy that contains 60% Gleason 4, 37% Gleason 3 and 3% Gleason 5 should get a score of 4 + 5 = 9. For details see (Epstein, 2016).\"</p>\n\n<p>Question : pattern 3 &lt; 5% then why gleason score will be 4+4 ? </p>",
      "rawMarkdown": "I am going through the explanation provided in additional resources and cannot comprehend below statement. \n\n\"The minority pattern must account for at least 5% of the total area to be included, e.g. if pattern 3 is less than 5%, the Gleason score 4 + 3 will instead be 4 + 4. Further, the highest grade should always be part of the score. For example, a biopsy that contains 60% Gleason 4, 37% Gleason 3 and 3% Gleason 5 should get a score of 4 + 5 = 9. For details see (Epstein, 2016).\"\n\nQuestion : pattern 3 &lt; 5% then why gleason score will be 4+4 ? ",
      "votes": 1
    },
    {
      "id": 865183,
      "postDate": "2020-05-28T13:01:16.963Z",
      "content": "<p>Thanks for clarifying !</p>",
      "rawMarkdown": "Thanks for clarifying !"
    }
  ],
  "comments": [
    {
      "id": 864918,
      "author_name": "Wouter Bulten",
      "author_url": "",
      "post_date": "2020-05-28T09:11:06.173000",
      "content": "<p>If the minority pattern takes up less than 5% of the tissue, you should not take it into account. In the example, &lt;5% is Gleason 3 and the rest is Gleason 4. In that case the Gleason score will be 4+4 because there is no other significant pattern.</p>\n\n<p>Edit: To clarify further, if there is a minor but higher pattern present (like 3% G5), it should always be included.</p>",
      "votes": 3,
      "replies": []
    },
    {
      "id": 865183,
      "author_name": "lincoln",
      "author_url": "",
      "post_date": "2020-05-28T13:01:16.963000",
      "content": "<p>Thanks for clarifying !</p>",
      "votes": 0,
      "replies": []
    }
  ],
  "raw_markdown_by_id": {
    "864918": "If the minority pattern takes up less than 5% of the tissue, you should not take it into account. In the example, &lt;5% is Gleason 3 and the rest is Gleason 4. In that case the Gleason score will be 4+4 because there is no other significant pattern.\n\nEdit: To clarify further, if there is a minor but higher pattern present (like 3% G5), it should always be included.",
    "863866": "I am going through the explanation provided in additional resources and cannot comprehend below statement. \n\n\"The minority pattern must account for at least 5% of the total area to be included, e.g. if pattern 3 is less than 5%, the Gleason score 4 + 3 will instead be 4 + 4. Further, the highest grade should always be part of the score. For example, a biopsy that contains 60% Gleason 4, 37% Gleason 3 and 3% Gleason 5 should get a score of 4 + 5 = 9. For details see (Epstein, 2016).\"\n\nQuestion : pattern 3 &lt; 5% then why gleason score will be 4+4 ? ",
    "865183": "Thanks for clarifying !"
  }
}